Effects of Experimental Sarcocystis neurona-Induced Infection on Immunity in an Equine Model
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چکیده
منابع مشابه
Effects of Experimental Sarcocystis neurona-Induced Infection on Immunity in an Equine Model
Sarcocystis neurona is the most common cause of Equine Protozoal Myeloencephalitis (EPM), affecting 0.5-1% horses in the United States during their lifetimes. The objective of this study was to evaluate the equine immune responses in an experimentally induced Sarcocystis neurona infection model. Neurologic parameters were recorded prior to and throughout the 70-day study by blinded investigator...
متن کاملExperimental Infection of Horses with Culture-Derived Sarcocystis neurona Merozoites as a Model for Equine Protozoal Myeloencephalitis
A study was designed to develop an experimental model to produce Sarcocystis neurona encephalitis in horses. Sarcocystis neurona, isolated from the spinal cord of an ataxic horse, was placed in continuous culture using bovine turbinate cells, and the cultured S. neurona merozoites were used to infect lymphocytes. A horse that was subsequently experimentally infected with 100,000 of the S. neuro...
متن کاملA review of Sarcocystis neurona and equine protozoal myeloencephalitis (EPM).
Equine protozoal myeloencephalitis (EPM) is a serious neurological disease of horses in the Americas. The protozoan most commonly associated with EPM is Sarcocystis neurona. The complete life cycle of S. neurona is unknown, including its natural intermediate host that harbors its sarcocyst. Opossums (Didelphis virginiana, Didelphis albiventris) are its definitive hosts. Horses are considered it...
متن کاملPenetration of equine leukocytes by merozoites of Sarcocystis neurona.
Horses are considered accidental hosts for Sarcocystis neurona and they often develop severe neurological disease when infected with this parasite. Schizont stages develop in the central nervous system (CNS) and cause the neurological lesions associated with equine protozoal myeloencephalitis. The present study was done to examine the ability of S. neurona merozoites to penetrate and develop in...
متن کاملAn equine protozoal myeloencephalitis challenge model testing a second transport after inoculation with Sarcocystis neurona sporocysts.
Previous challenge studies performed at Ohio State University involved a transport-stress model where the study animals were dosed with Sarcocystis neurona sporocysts on the day of arrival. This study was to test a second transportation of horses after oral inoculation with S. neurona sporocysts. Horses were assigned randomly to groups: group 1, transported 4 days after inoculation (DAI); group...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medicine
سال: 2014
ISSN: 2356-7708,2314-6966
DOI: 10.1155/2014/239495